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Preimplantation Genetic Testing

Higher Success Rates with PGT

Combining IVF or ICSI with preimplantation genetic testing (PGT) increases your chances of pregnancy and lowers the risk of miscarriage. Experienced specialists are there to support you throughout the entire process.

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No long waiting times

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In-house lab

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Holistic care

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Transparent costs

What is PGT?

Preimplantation genetic testing (PGT) analyses embryos created through IVF or ICSI for genetic conditions before transfer to the uterus.

This allows for the selection of embryos with a reduced risk of specific genetic conditions, minimising the likelihood of serious inherited diseases in the child.

Who benefits from PGT?

Many factors influence a couple's decision to pursue PGT. In consultation with our specialists, we can help you determine the most appropriate genetic testing for your specific situation.

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Couples with failed IVF/ICSI cycles

PGT detects chromosomal abnormalities in embryos that may lead to repeated pregnancy loss or failed IVF/ICSI cycles.

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Couples with a known genetic condition

PGT screens embryos for specific genetic disorders, including cystic fibrosis and Huntington's disease.

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Women over 35 years

PGT reduces age-related chromosomal risks, improving healthy pregnancy outcomes.

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PGT: Step-by-Step

After egg retrieval and fertilization via IVF or ICSI, the embryos are cultured for five to six days. A biopsy is then performed before they are cryopreserved and sent to our partner laboratory, Genetica, for genetic analysis. We then discuss the results and plan the next steps.

Step 1

Genetic Counseling

Comprehensive genetic counseling is the initial step. We gather the couple's family medical history and determine the most suitable genetic tests.

Step 2

IVF/ICSI and Embryo Biopsy

Following hormonal stimulation, eggs are retrieved and fertilized via IVF or ICSI in the laboratory. Embryos are cultured, and on day 3 or 5, individual cells are biopsied for genetic testing.

Step 3

Genetic Analysis

The biopsied cells undergo genetic analysis in the laboratory. The results are then carefully reviewed and interpreted.

Step 4

Embryo Transfer

Based on the PGT results, a healthy embryo is selected and transferred into the uterus. Remaining healthy embryos are cryopreserved for future use.

Step 5

Pregnancy Test

A pregnancy test is performed approximately two weeks after embryo transfer. If pregnancy is confirmed, further prenatal testing (e.g., ultrasound, chorionic villus sampling, amniocentesis) may be recommended.

Benefits of PGT with Cada

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Increased pregnancy success

PGT allows for the selection of genetically healthy embryos, significantly enhancing the likelihood of a successful pregnancy.

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Reduced risk of miscarriage

By analysing embryos prior to transfer, we identify and exclude those with chromosomal abnormalities, a leading cause of miscarriage.

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Prevention of hereditary diseases

We analyze embryos to ensure transfer of those without specific genetic abnormalities, reducing hereditary disease risk.

Desire to have children over 40

Why PID is particularly useful from the age of 40 onwards

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From the age of 40 onwards, the risk of chromosomal abnormalities in embryos increases significantly. This often leads to unsuccessful transfers or miscarriages.

With PGD, embryos can be genetically tested before transfer and only those with an intact chromosome set can be transferred. This increases the chances of a successful pregnancy and significantly reduces the risk of miscarriage.

Our Location

Our Clinic in Zurich

At the modern Cada Clinic, located directly on Lake Zurich, you'll find fertility treatments such as IVF, ICSI, and social freezing.

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    All experts in one place

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    Peaceful location in Zurich Seefeld

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    On-site IVF laboratory

Free consultation

We’re happy to answer your questions

Email

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Feel free to send us an email with your questions. We usually respond the same day.

Call us

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You can reach us by phone on working days from 8:00 AM to 1:00 PM and 2:00 PM to 5:30 PM.

Appointment

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You will learn more about your treatment at Cada in a consultation appointment.

Frequently Asked Questions (FAQ)

Discover answers to the most common queries about PGT here. Should your question remain unresolved, please do not hesitate to reach out to us directly.

Is pre-implantation genetic testing permitted in Switzerland?

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Preimplantation genetic testing (PGT) is permitted in Switzerland if there is a high risk of a serious hereditary disease or chromosomal disorder that cannot be prevented in any other way. It is also permitted for couples who cannot conceive naturally or who have already experienced several miscarriages.

Couples must undergo genetic counselling and the procedure must be approved by an ethics committee.

PGT may only be carried out in specialised centres, whereby the number of fertilised eggs is limited and only embryos up to a certain stage of development may be examined.

What is the cost of preimplantation genetic diagnosis?

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The cost of PGT depends on the type of genetic test and the number of embryos that are analysed. At Cada, the fees consist of a basic fee per cycle plus a fee per embryo.

  • PGT-A and PGT-SR: CHF 950 basic fee plus CHF 600 per tested embryo
  • PGT-M: Price on request, depending on the genetic question and the complexity of the test development

PGT costs are in addition to the expenses for IVF or ICSI and medication. During your consultation, we are happy to provide a clear, personalised cost estimate for your situation.

When is it useful to carry out preimplantation genetic diagnosis?

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PGD can be useful if there is an increased risk of genetic diseases or chromosomal disorders in the child. This is the case, for example, if

  • one or both parents are carriers of a genetic disease.
  • a child has already been born with a genetic disorder.
  • the woman is over 35 years old, as the risk of chromosomal disorders increases as the mother gets older.
  • there is a history of several miscarriages.
  • several unsuccessful IVF attempts have been undertaken.

How safe is preimplantation genetic diagnosis?

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PGD is a very safe method, but not a 100% guarantee. The accuracy of the diagnosis is over 99%. In rare cases, it can happen that a genetic change is overlooked or that an embryo is wrongly categorised as diseased.

For whom is genetic testing of the embryo recommended?

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Genetic testing of the embryo can be worthwhile for couples who have an increased risk of genetic diseases or chromosomal disorders in the child. It can help to increase the probability of a pregnancy with a healthy child and reduce the risk of miscarriage.

How does pre-implantation genetic testing work?

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PGD comprises various procedures:

  • PGT-A (pre-implantation genetic testing for aneuploidy): This involves analysing the number and structure of the embryo's chromosomes. Aneuploidies are numerical chromosomal abnormalities that can lead to miscarriages or genetic diseases such as trisomy 21 (Down's syndrome).
  • PGT-M (pre-implantation genetic testing for monogenetic diseases): This involves a targeted search for a specific genetic change that causes a monogenetic disease, e.g. cystic fibrosis or Huntington's disease.
  • PGT-SR (pre-implantation genetic testing for structural chromosomal abnormalities): This examines structural changes in the chromosomes, e.g. translocations or inversions.

Are the costs of pre-implantation genetic diagnosis covered by health insurance?

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The costs of PGD are not covered by compulsory health insurance (OKP) in Switzerland. Any assumption of costs by the health insurance fund must be checked on a case-by-case basis.

Does PGT replace prenatal testing in pregnancy, such as NIPT or the first trimester test?

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No. PGT can lower the risk of certain genetic conditions and miscarriages, but it does not replace prenatal diagnostics during pregnancy. We still recommend the usual pregnancy check ups after PGT. This includes ultrasound scans, the first trimester test and, if needed, NIPT or further tests to monitor your baby’s development.

Can I use PGT to choose the sex of my baby?

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No. In Switzerland it is legally forbidden to choose the sex of a child for non medical reasons.

How high are my chances of success with PGT, especially if I am over 35?

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PGT can improve the chances of an IVF treatment, especially for women over 35, for couples with repeated miscarriages or with known genetic problems. By excluding embryos with clear chromosomal errors, PGT can increase implantation rates and reduce miscarriage rates.

Your individual chances depend on several factors, such as your age, your ovarian reserve, sperm quality and any existing medical conditions. We discuss these factors in detail with you during the first consultation.

How are our genetic data and embryos protected at Cada?

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Your genetic data and results are stored according to strict data protection regulations and are only accessible to the healthcare professionals directly involved in your care. Embryos are stored in our IVF laboratory under controlled conditions using cryopreservation. They are only used further or discarded with your written consent.

Schedule your consultation now

During a free initial consultation, we take the time to comprehend your needs and offer informed advice on your available options.

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